3/3/2023 0 Comments Nsss 6th edition free pdf![]() ![]() No evidence of any effect of NSSs was seen on overweight or obese adults or children actively trying to lose weight (very low to moderate certainty). For all other outcomes, no differences were detected between the use and non-use of NSSs, or between different doses of NSSs. ![]() Lower doses of NSSs were associated with lower weight gain (−0.09 kg, −0.13 to −0.05 one, n=17 934) compared with higher doses of NSSs (very low certainty of evidence). In adults, evidence of very low and low certainty from a limited number of small studies indicated a small beneficial effect of NSSs on body mass index (mean difference −0.6, 95% confidence interval −1.19 to −0.01 two studies, n=174) and fasting blood glucose (−0.16 mmol/L, −0.26 to −0.06 two, n=52). Of 56 individual studies that provided data for this review, 35 were observational studies. The search resulted in 13 941 unique records. NSSs had to be clearly named, the dose had to be within the acceptable daily intake, and the intervention duration had to be at least seven days.īody weight or body mass index, glycaemic control, oral health, eating behaviour, preference for sweet taste, cancer, cardiovascular disease, kidney disease, mood, behaviour, neurocognition, and adverse effects. ![]() Included study designs allowed for a direct comparison of no intake or lower intake of NSS with higher NSS intake. Studies including generally healthy adults or children with or without overweight or obesity were eligible. Medline (Ovid), Embase, Cochrane CENTRAL, WHO International Clinical Trials Registry Platform,, and reference lists of relevant publications.Įligibility criteria for selecting studies Systematic review following standard Cochrane review methodology. To assess the association between intake of non-sugar sweeteners (NSS) and important health outcomes in generally healthy or overweight/obese adults and children. ![]()
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